The AIVO database is a retrospective “pseudo-biobank” type collection of brain scans acquired at the Turku University Hospital and Turku PET Centre. This project is conducted in the context of register study, and the image data are linked with a variety of medical and socioeconomic registers.

Because the image data have to be identified and processed retrospectively, the database is constantly updated. Below is a summary of the images we have in the database so far, grouped by higher-order systems under scrutiny. The Available scans column indicates the total number of scans theoretically available for each ligand. The Processed scans column indicates the number of scans that have been evaluated as adequate for inclusion in the database, and that has subsequently been processed with the MAGIA pipeline.

Database completion

Systems-level group	System-level scan count	Targets	Scan type	Available scans	Processed scans
Brain structure	89,284	Atrophy	T1 MRI	89,284	5,110

Tau pathology	1,953	Beta-amyloid	[11C]-PIB	1,798	744
		Beta-amyloid	[18F]-flutemetamol	155	0

Neuronal activity	8,809	Glucose uptake	[18F]-FDG	3,848	1,197
		Perfusion	[15O]-H2O	4,961	0

Dopamine system	3,290	D2R	[11C]-raclopride	1,468	1057
		Dopamine system	[18f]-DOPA	995	692
		D2D3R	[11C]-FLB	387	1
		Dopamine reuptake	[18F]-CFT	324	0
		DR	[11C]-NNC	116	0

Opioid system	713	MOR	[11C]-Carfentanil	713	626

Inflammation	609	Inflammation	[11C]-PBR28	272	177
		Inflammation	[11C]-PK11195	337	139

Serotonin system	271	5HT1A	[11C]-WAY	141	0
		SERT	[11C]-MADAM	130	72

updated: 13.2.2023