Brain Scans

The AIVO database is a retrospective “pseudo-biobank” type collection of brain scans acquired at the Turku University Hospital and Turku PET Centre. This project is conducted in the context of register study, and the image data are linked with a variety of medical and socioeconomic registers.

Because the image data have to be identified and processed retrospectively, the database is constantly updated. Below is a summary of the images we have in the database so far, grouped by higher-order systems under scrutiny. The Available scans column indicates the total number of scans theoretically available for each ligand. The Processed scans column indicates the number of scans that have been evaluated as adequate for inclusion in the database, and that has subsequently been processed with the MAGIA pipeline.

Database completion

Systems-level group
System-level scan count Targets Scan type Available scans Processed scans
Brain structure 89,284 Atrophy T1 MRI 89,284 5,110
Tau pathology  1,953 Beta-amyloid [11C]-PIB 1,798 744
Beta-amyloid [18F]-flutemetamol 155 0
Neuronal activity 8,809 Glucose uptake [18F]-FDG 3,848 1,197
Perfusion [15O]-H2O 4,961 0
Dopamine system 3,290 D2R [11C]-raclopride 1,468 1057
Dopamine system [18f]-DOPA 995 692
D2D3R [11C]-FLB 387 1
Dopamine reuptake [18F]-CFT 324 0
DR [11C]-NNC 116 0
Opioid system 713 MOR [11C]-Carfentanil 713 626
Inflammation 609 Inflammation [11C]-PBR28 272 177
Inflammation [11C]-PK11195 337 139
Serotonin system 271 5HT1A [11C]-WAY 141 0
SERT [11C]-MADAM 130 72

updated: 13.2.2023